論文発表

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2021年

◆Teoh SH, Miyajima K, Shinozaki Y, Shinohara M, Ohata K, Briand F, Morimoto R, Nakamura Y, Uno K, Kemuriyama N, Nakae D, Ohta T, Maekawa T
Effects of excessive sodium chloride loading in the spontaneously diabetic torii (SDT) fatty rats, a preclinical model of type 2 diabetes mellitus
J. Toxicol. Sci., in press.

◆Okunomiya A, Horie A, Tani H, Sato Y, Takamatsu S, Brown JB, Sugimoto M, Hamanishi J, Kondoh E, Matsumura N, Mandai M
Figla promotes secondary follicle growth in mature mice.
Sci. Rep., 2021; 11:9842.

◆Fatchiyah F, Setiawan B, Sasase T, Ohta T
The amelioration of T2DM rat femoral bone achieved by anti-osteoporosis of caprine CSN1S2 protein through bone morphogenetic protein signaling pathway
Acta Biochim. Pol., 2021; 68(2):265-275.

◆Maekawa T, Nakamura S, Miyajima K, Uno K, Yamaguchi A, Mandai K, Gotoh T, Shinohara M, Shinozaki Y, Sasase T, Fatchiyah F, Ohta T
Ocular changes -cataract and retinal lesion- in Spontaneously Diabetic Torii (SDT) fatty rats, an obese type 2 diabetic model
JSMARTech., 2021; 2(2):81-86.

◆Sasase T, Ito M, Ishii Y, Ohta T
Bilateral midbrain transection induced hyperphagia accelerates the development of diabetes in Spontaneously Diabetic Torii (SDT) rats
JSMARTech., 2021; 2(2):69-74.

◆Wada M, Yukawa K, Ogasawara H, Suzawa K, Maekawa T, Yamamoto Y, Ohta T, Lee E, Miki T
GPR52 accelerates fatty acid biosynthesis in a ligand-dependent manner in hepatocytes and in response to excessive fat intake in mice
iScience., 2021; 24:102260.

◆Kurimoto T, Tamai I, Nakagawa T, Miyai A, Yamamoto Y, Kosugi Y, Deai K, Hata T, Ohta T, Matsushita M, Yamada T
JTP-117968, a novel selective glucocorticoid receptor modulator, exhibits significant anti-inflammatory effect while maintaining bone mineral density in mice
Eur. J. Pharmacol., 2021; 895:173880.

◆Sano R, Ishi Y, Yamanaka M, Yasui Y, Kemmochi Y, Kuroki F, Sugimoto M, Fukuda S, Sasase T, Miyajima K, Nakae D, Ohta T
Glomerular hyperfiltration with hyperglycemia in the Spontaneously Diabetic Torii (SDT) fatty rat, an obese type 2 diabetic model
Physiol. Res., 2021; 70:45-54.

◆Tadaki H, Ogawa N, Yamanaka M, Motohashi Y, Sasase T, Kawai T, Toriniwa Y, Fukuda S, Ogawa N, Harada K, Ohta T, Yamada T
JTP-109192, a novel G-protein coupled receptor 119 agonist, prevents atherosclerosis by improving hypercholesterolemia in congenic spontaneously hyperlipidaemic mice.
Clin. Exp. Pharmacol. Physiol., 2021; 48:381-388.

◆Kobayashi K, Sasase T, Ishii Y, Katsuda Y, Miyajima K, Yamada T, Ohta T
The sphingosine-1-phosphate receptor modulator, FTY720, prevents the incidence of diabetes in Spontaneously Diabetic Torii rats.
Clin. Exp. Pharmacol. Physiol., 2021; 48(6):869-876.

  

◆山本修平・稲葉信博・前野孝之・平尾直啓・山中沙織・篠崎雄一・太田毅
ケージ内環境変化に伴うラットの居住性評価方法の確立
実験動物技術, 2021; 56(1):7-14

          

2020年

◆Fatchiyah F, Rohmah RN, Tripsila LF, Ohta T, Meidinna HN
The Caprine casein-alpha-S2 protein modulates the molecular mechanism of insulin signal transduction in Type2 diabetes rat.
Acta Biochim. Pol., 2020; 67:401-408.

◆Ishitani H, Ikeda S, Egashira K, Sugimoto M, Kume S, Minami N, Ohta T
Embryonic MTHFR contributes to blastocyst development.
J. Assist. Reprod. Genet., 2020; 37:1807-1814.

◆Sano R, Shinozaki Y, Ohta T
Sodium glucose co-transporters: functional properties and pharmaceutical potential.
J. Diabetes Investig., 2020; 11:770-782.

◆Nakane Y, Kemmochi Y, Ogawa N, Sasase T, Ohta T, Higami Y, Fukai F
Hyperglycemia contributes to a development of leydig cell hyperplasia in male Spontaneously Diabetic Torii rats.
J. Toxicol. Pathol., 2020; 33:121-129.

◆Iida A, Matsushita M, Ohta T, Yamada T
Conventional and novel impacts of ferric citrate on iron deficiency anemia and phosphorus metabolism in rats.
J. Vet. Med. Sci., 2020; 82(3):379-386.

◆Murai Y, Sasase T, Tadaki H, Heitaku S, Imagawa N, Yamada T, Ohta T
Analysis of haemodynamics and angiogenic response to ischaemia in the obese type 2 diabetic model Spontaneously Diabetic Torii Leprfa (SDT fatty) rats.
Clin. Exp. Pharmacol Physiol., 2020; 47:583-590.

            

2019年

◆Yamada T, Nagata H, Ikenori D, Taniguchi Y, Ohta T, Sugiyama T, Homma K, Kaneko Y, Iwaisaki H
Molecular assessment of genetic diversity in the Japanese population of the Japanese crested ibis.
Ornitholog. Sci., in press.

◆Maekawa M, Tadaki H, Tomimoto D, Okuma C, Sano R, Ishii Y, Katsuda Y, Yoshiuchi H, Kakefuda R, Ohta T, Sasae T
A novel TNF-α converting enzyme (TACE) selective inhibitor JTP-96193 prevents insulin resistance in KK-Ay Type 2 diabetic mice and diabetic peripheral neuropathy in type 1 diabetic mice.
Biol. Pharm. Bull., 2019; 42(11):1906-1912.

◆Tadaki H, Sasase T, Fukuda S, Toriniwa Y, Harada K, Ohta T, Yamada T
Chronic treatment of JTP-109192, a novel G-protein coupled receptor 119 agonist, improves metabolic abnormalities in Zucker Fatty rats.
Clin. Exp. Pharmacol. Physiol., 2019; 46:910-919.

◆Tanaka Y, Takagi R, Ohta T, Sasase T, Kobayashi M, Toyoda F, Shimmura M, Kinoshita N, Takano H, Kakehashi A
Pathological features of diabetic retinopathy in Spontaneously Diabetic Torii fatty rats.
J. Diabetes Res., 2019; 8724818.

◆Fatchiyah F, Nurmasari DA, Masruro N, Rohmah RN, Triprisila LF, Mulyati M, Yamada T, Ohta T
Level of mRNA insulin gene and blood glucose STZ-induced diabetic rat are improved by glucomannan of amorphophallus muelleri blume from East Java forest Indonesia.
J. Trop. Life Sci., 2019; 9(2):163-169.

      

◆鳥庭靖文・斉藤友幸・谷合枝里子・石井幸仁・美谷島克宏・前川竜也・篠原雅巳・山田宜永・太田毅
Quick Fat 食給餌が肥満2型糖尿病モデル SDT fatty ラットの肝臓に及ぼす影響
北信越畜産学会報 2019; 118:1-8.

◆斉藤友幸・鳥庭靖文・石井幸仁・美谷島克宏・前川竜也・植村淳弘・篠原雅巳・山田宜永・太田毅
コレステロール負荷 Zucker fatty ラット肝臓の病態生理学的変化
北信越畜産学会報 2019; 118:9-15.

◆前川麻梨子・唯木洋暢・勝田佳朋・篠原雅巳・美谷島克宏・山田宜永・太田毅
肥満2型糖尿病モデル動物 SDT fatty ラットの腸管病理解析
北信越畜産学会報 2019; 118:17-24.

    

~2018年

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